TdT Mouse anti-Mouse, PE, Clone: 19-3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5846-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15288849

Quantity Price
1 £ 78.88 / 25µg
EU Stock 4
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Description and Specification

Specification

Species Reactivity Mouse
Format Conjugated
Applications Flow Cytometry (Intracellular Staining)
Conjugate PE
Regulatory Status RUO
Host Species Mouse
Isotype IgG2b
Quantity 25μg
Clone 19-3
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Gene Alias terminal deoxynucleotidyl transferase
Monoclonal or Polyclonal Monoclonal
Antigen TdT
Primary or Secondary Primary
Concentration 0.2mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

This 19-3 monoclonal antibody recognizes human and mouse terminal-deoxynucleotidyl transferase (TdT), a 60kDa polymerase responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. Expression is found in the nucleus of immature lymphocytes but not in mature lymphocytes or non-lymphoid cells. Tdt plays a critical role during TCR and Ig gene rearrangement. Regulation of expression in the mouse thymus correlates with T cell selection; decreased or absent after positive selection. Additionally Tdt has been shown to be present in lymphoma or lymphoblastic leukemia cells.