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TCS PrP Inhibitor 13, Tocris Bioscience™

Antiprion agent; inhibits PrPSc accumulation

Brand:  Tocris (Bio-Techne) 323810

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13442624

  • £127.89 / 10mg

Estimated Shipment date
from Supplier 28-10-2019

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Description

Description

Antiprion agent. Potently inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblastoma (N2a) cell lines (IC50 = 3 nM). Also reduces PrP expression and decreases proliferation and survival in schwannoma cell lines.
Specifications

Chemical Identifiers

34320-83-7
281.271
tcs prp inhibitor 13, 5-4-nitrophenyl-2-phenyl-4h-pyrazol-3-one, 3h-pyrazol-3-one, 2,4-dihydro-5-4-nitrophenyl-2-phenyl, 1-phenyl-3-4-nitrophenyl-2-pyrazolin-5-one, 3-4-nitrophenyl-1-phenyl-1h-pyrazol-5 4h-one, 5-4-nitrophenyl-2-phenyl-2,4-dihydro-3h-pyrazol-3-one, 2,4-dihydro-5-4-nitrophenyl-2-phenyl-3h-pyrazol-3-one
5-(4-nitrophenyl)-2-phenyl-4H-pyrazol-3-one
C15H11N3O3
FDAVFKZPGQEGDX-UHFFFAOYSA-N
2750328
C1C(=NN(C1=O)C2=CC=CC=C2)C3=CC=C(C=C3)[N+](=O)[O-]

Specifications

10mg
34320-83-7
tcs prp inhibitor 13, 5-4-nitrophenyl-2-phenyl-4h-pyrazol-3-one, 3h-pyrazol-3-one, 2,4-dihydro-5-4-nitrophenyl-2-phenyl, 1-phenyl-3-4-nitrophenyl-2-pyrazolin-5-one, 3-4-nitrophenyl-1-phenyl-1h-pyrazol-5 4h-one, 5-4-nitrophenyl-2-phenyl-2,4-dihydro-3h-pyrazol-3-one, 2,4-dihydro-5-4-nitrophenyl-2-phenyl-3h-pyrazol-3-one
C1C(=NN(C1=O)C2=CC=CC=C2)C3=CC=C(C=C3)[N+](=O)[O-]
281.271
281.27
TCS PrP Inhibitor 13
C15H11N3O3
FDAVFKZPGQEGDX-UHFFFAOYSA-N
5-(4-nitrophenyl)-2-phenyl-4H-pyrazol-3-one
2750328
>98%
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