Tocris Bioscience™ TCS PIM-1 4a

Selective, ATP-competitive Pim kinase inhibitor

Description

Selective, ATP-competitive Pim kinase inhibitor (IC50 values are 24 and 100 nM for Pim-1 and Pim-2 respectively). Displays selectivity over a panel of ∽50 other kinases tested. Exhibits cytotoxicity in PC3 prostate carcinoma cells in vitro (IC50 = 17 μM).

Specifications

• Purity: >98%

For Research Use Only