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TB 21007, Tocris Bioscience™

α5-selective GABAA inverse agonist

Brand:  Tocris (Bio-Techne) 290550

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462014

  • £578.52 / 50mg


Estimated Shipment
03-12-2018
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Description

Description

GABAA receptor inverse agonist selective for the α5-subtype (Ki values are 1.6, 16, 20 and 20 nM for α5, α2, α1 and α3 subtypes respectively). Brain penetrant; enhances cognitive performance in rats in the delayed matching-to-place morris water maze test following i.p. administration.
Specifications

Chemical Identifiers

207306-50-1
339.486
chembl17603, 3-2-hydroxyethyl sulfanyl-6,6-dimethyl-1-1,3-thiazol-2-yl-5,7-dihydro-2-benzothiophen-4-one, 6,7-dihydro-3-2-hydroxyethyl thio-6,6-dimethyl-1-2-thiazolyl-benzo c thiophen-4 5h-one, 1-2-thiazolyl-3-2-hydroxyethylthio-6,6-dimethyl-6,7-dihydrobenzo c thiophene-4 5h-one, 3-2-hydroxy-ethylsulfanyl-6,6-dimethyl-1-thiazol-2-yl-6,7-dihydro-5h-benzo c thiophen-4-one, 3-2-hydroxyethylsulfanyl-6,6-dimethyl-1-1,3-thiazol-2-yl-5,7-dihydro-2-benzothiophen-4-one
3-(2-hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
C15H17NO2S3
QILRYFCEXLFIDS-UHFFFAOYSA-N
6918633
CC1(CC2=C(SC(=C2C(=O)C1)SCCO)C3=NC=CS3)C

Specifications

TB 21007
207306-50-1
chembl17603, 3-2-hydroxyethyl sulfanyl-6,6-dimethyl-1-1,3-thiazol-2-yl-5,7-dihydro-2-benzothiophen-4-one, 6,7-dihydro-3-2-hydroxyethyl thio-6,6-dimethyl-1-2-thiazolyl-benzo c thiophen-4 5h-one, 1-2-thiazolyl-3-2-hydroxyethylthio-6,6-dimethyl-6,7-dihydrobenzo c thiophene-4 5h-one, 3-2-hydroxy-ethylsulfanyl-6,6-dimethyl-1-thiazol-2-yl-6,7-dihydro-5h-benzo c thiophen-4-one, 3-2-hydroxyethylsulfanyl-6,6-dimethyl-1-1,3-thiazol-2-yl-5,7-dihydro-2-benzothiophen-4-one
CC1(CC2=C(SC(=C2C(=O)C1)SCCO)C3=NC=CS3)C
339.486
339.5
50mg
C15H17NO2S3
QILRYFCEXLFIDS-UHFFFAOYSA-N
3-(2-hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
6918633
>99%
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