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T16Ainh - A01, Tocris Bioscience™

Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor

Brand:  RD Systems (Bio-Techne) 4538/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

 View more versions of this product

Product Code. 13444904

  • £618.87 / 50mg

Estimated Shipment date
from Supplier 17-12-2019

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Description

Description

Inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 μM in A253 salivary gland epithelial cells). Inhibits EGF-induced increases in CaCC currents; blocks proliferation of tumor cells in vitro.
Specifications

Chemical Identifiers

552309-42-9
416.514
t16a inh-a01, t16ainh-a01, 2-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl thio-n-4-4-methoxyphenyl thiazol-2-yl acetamide, 2-5-ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl thio-n-4-4-methoxyphenyl-2-thiazolyl acetamide, 2-5-ethyl-4-hydroxy-6-methylpyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, t16ainh-a hplc, 2-5-ethyl-4-hydroxy-6-methylpyrimidin-2-ylthio-n-4-4-methoxyphenyl thiazol-2-yl acetamide, 2-5-ethyl-4-methyl-6-oxo-3h-pyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, 2-5-ethyl-6-methyl-4-oxo-1h-pyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, n-4-4-methoxyphenyl thiazole-2-yl-2-4-hydroxy-5-ethyl-6-methylpyrimidine-2-ylthio acetamide
2-[(5-ethyl-6-methyl-4-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide
C19H20N4O3S2
QSIYTNYMBWYHAA-UHFFFAOYSA-N
3193184
CCC1=C(NC(=NC1=O)SCC(=O)NC2=NC(=CS2)C3=CC=C(C=C3)OC)C

Specifications

50mg
552309-42-9
t16a inh-a01, t16ainh-a01, 2-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl thio-n-4-4-methoxyphenyl thiazol-2-yl acetamide, 2-5-ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl thio-n-4-4-methoxyphenyl-2-thiazolyl acetamide, 2-5-ethyl-4-hydroxy-6-methylpyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, t16ainh-a hplc, 2-5-ethyl-4-hydroxy-6-methylpyrimidin-2-ylthio-n-4-4-methoxyphenyl thiazol-2-yl acetamide, 2-5-ethyl-4-methyl-6-oxo-3h-pyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, 2-5-ethyl-6-methyl-4-oxo-1h-pyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, n-4-4-methoxyphenyl thiazole-2-yl-2-4-hydroxy-5-ethyl-6-methylpyrimidine-2-ylthio acetamide
CCC1=C(NC(=NC1=O)SCC(=O)NC2=NC(=CS2)C3=CC=C(C=C3)OC)C
416.514
416.52
T16Ainh - A01
C19H20N4O3S2
QSIYTNYMBWYHAA-UHFFFAOYSA-N
2-[(5-ethyl-6-methyl-4-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide
3193184
>98%
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