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SYM 2206, Tocris Bioscience™

Non-competitive AMPA antagonist

Brand:  Tocris (Bio-Techne) 096110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13488203

  • £170.28 / 10mg


Estimated Shipment
04-10-2018
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Description

Description

Novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). Acts allosterically at the same regulatory site as GYKI 52466 and 53655 and other benzodiazepines but does not bind to the central diazepine binding site. Selective for AMPA relative to kainate receptor sub-types. Similar potency to GYKI 53655. Anticonvulsant in vivo.
Specifications

Chemical Identifiers

173952-44-8
366.421
(±)-4-(4-Aminophenyl)-1, 2-dihydro-1-methyl-2-propylcarbamoyl-6, 7-methylenedioxyphthalazine
C20H22N4O3
OFUDZKKOKPGXOH-UHFFFAOYSA-N
5039877

Specifications

SYM 2206
>99%
C20H22N4O3
OFUDZKKOKPGXOH-UHFFFAOYSA-N
8-(4-aminophenyl)-5-methyl-N-propyl-5H-[1,3]dioxolo[4,5-g]phthalazine-6-carboxamide
5039877
173952-44-8
10mg
(±)-4-(4-Aminophenyl)-1, 2-dihydro-1-methyl-2-propylcarbamoyl-6, 7-methylenedioxyphthalazine
CCCNC(=O)N1C(C2=CC3=C(C=C2C(=N1)C4=CC=C(C=C4)N)OCO3)C
366.421
366.42
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