STOML2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA563999

Product Code. 15791762

Description

Immunogen sequence: RESLNASIVD AINQAADCWG IRCLRYEIKD IHVPPRVKES MQMQVEAERR KRATVLESEG TRESAINVAE G Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.

Specifications

• Antigen: STOML2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Stoml2
• Gene Alias: 0610038F01Rik; EPB72-like 2; EPB72-like protein 2; HSPC108; MSLP2; Paraprotein target 7; paratarg-7; Slp2; SLP-2; stomatin (Epb7.2)-like 2; stomatin (EPB72)-like 2; stomatin like 2; stomatin-like 2; stomatin-like protein 2, mitochondrial; Stoml2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30968
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UJZ1
• Gene Symbols: Stoml2
• Immunogen: Recombinant protein corresponding to Human STOML2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only