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STF 083010, Tocris Bioscience™

Inhibits IRE1α endonuclease activity

Brand:  RD Systems (Bio-Techne) 4509/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

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Product Code. 13434854

  • £710.01 / 50mg

Estimated Shipment date
from Supplier 19-11-2019

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Description

Description

Inhibitor of IRE1α endonuclease activity; blocks endogenous XBP1 mRNA splicing. Displays cytostatic and cytotoxic effects in CD138+ multiple myeloma (MM) cells in vitro; inhibits bortezomib-induced XBP1 activity in myeloma xenografts in vivo. Does not alter IRE1α kinase activity.
Specifications

Chemical Identifiers

307543-71-1
317.377
regid_for_cid_6537512, stf hplc, n-2-hydroxy-1-naphthyl methylene-2-thiophenesulfonamide, e-n-2-hydroxynaphthalen-1-yl methylene thiophene-2-sulfonamide, n-z-2-oxonaphthalen-1-ylidene methyl thiophene-2-sulfonamide
N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]thiophene-2-sulfonamide
C15H11NO3S2
AUXKGDNZANYAPX-RAXLEYEMSA-N
6537512
C1=CC=C2C(=C1)C=CC(=O)C2=CNS(=O)(=O)C3=CC=CS3

Specifications

50mg
307543-71-1
regid_for_cid_6537512, stf hplc, n-2-hydroxy-1-naphthyl methylene-2-thiophenesulfonamide, e-n-2-hydroxynaphthalen-1-yl methylene thiophene-2-sulfonamide, n-z-2-oxonaphthalen-1-ylidene methyl thiophene-2-sulfonamide
C1=CC=C2C(=C1)C=CC(=O)C2=CNS(=O)(=O)C3=CC=CS3
317.377
317.38
STF 083010
C15H11NO3S2
AUXKGDNZANYAPX-RAXLEYEMSA-N
N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]thiophene-2-sulfonamide
6537512
>98%
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