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SSR 146977 hydrochloride, Tocris Bioscience™

Potent and selective NK3 antagonist

Brand:  Tocris (Bio-Techne) 329710

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13442734

  • £198.45 / 10mg

Estimated Shipment date
from Supplier 20-12-2019

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Description

Description

Potent and selective NK3 receptor antagonist (Ki values are 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor respectively). Also inhibits senktide -induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM).
Specifications

Chemical Identifiers

264618-38-4
658.105
ssr 146977 hydrochloride, ssr 146977 hydrochloride/ssr-146977, n1-1-3-3r-1-benzoyl-3-3-3,4-dichlorophenyl-3-piperidinyl propyl-4-phenyl-piperidinyl-n,n-dimethylurea hydrochloride
3-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-1,1-dimethylurea;hydrochloride
C35H43Cl3N4O2
HYPKKQPFHSNZBY-GXUZKUJRSA-N
90488827
CN(C)C(=O)NC1(CCN(CC1)CCCC2(CCCN(C2)C(=O)C3=CC=CC=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=CC=C5.Cl

Specifications

10mg
264618-38-4
ssr 146977 hydrochloride, ssr 146977 hydrochloride/ssr-146977, n1-1-3-3r-1-benzoyl-3-3-3,4-dichlorophenyl-3-piperidinyl propyl-4-phenyl-piperidinyl-n,n-dimethylurea hydrochloride
CN(C)C(=O)NC1(CCN(CC1)CCCC2(CCCN(C2)C(=O)C3=CC=CC=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=CC=C5.Cl
658.105
658.11
SSR 146977 hydrochloride
C35H43Cl3N4O2
HYPKKQPFHSNZBY-GXUZKUJRSA-N
3-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-1,1-dimethylurea;hydrochloride
90488827
>98%
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