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SR 142948, Tocris Bioscience™

Highly potent NTS receptor antagonist

Brand:  RD Systems (Bio-Techne) 23091

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 1mg

 View more versions of this product

Product Code. 13441004

  • £144.06 / 1mg

Estimated Shipment date
from Supplier 20-11-2019

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Description

Description

Potent non-peptide neurotensin (NT) receptor antagonist that binds with high affinity (IC50 = 0.32 - 3.96 nM; Ki < 10 nM). Attenuates amphetamine-induced hyperactivity and is orally active in vivo.
Specifications

Chemical Identifiers

184162-64-9
685.866
d0oj7s, sr 142948 hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methylamino carbonyl-2-1-methylethyl phenyl-1h-pyrazol-3-yl carbonyl amino-tricyclo 3.3.1.13,7 decane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-3-dimethylaminopropyl-n-methylcarbamoyl-2-isopropylphenyl-1h-pyrazole3-carbonyl amino adamantane-2-carboxylic acid hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylaminopropyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methyl carbamoyl-2-isopropylphenyl pyrazole-3-amido adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-methyl-n-3-dimethylaminopropyl carbamoyl-2-isopropylphenyl-3-pyrazolylcarbonylamino-2-adamantanecarboxylic acid
2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methylcarbamoyl]-2-propan-2-ylphenyl]pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid
C39H51N5O6
LWULHXVBLMWCHO-UHFFFAOYSA-N
5311451
CC(C)C1=C(C=CC(=C1)C(=O)N(C)CCCN(C)C)N2C(=CC(=N2)C(=O)NC3(C4CC5CC(C4)CC3C5)C(=O)O)C6=C(C=CC=C6OC)OC

Specifications

1mg
184162-64-9
d0oj7s, sr 142948 hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methylamino carbonyl-2-1-methylethyl phenyl-1h-pyrazol-3-yl carbonyl amino-tricyclo 3.3.1.13,7 decane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-3-dimethylaminopropyl-n-methylcarbamoyl-2-isopropylphenyl-1h-pyrazole3-carbonyl amino adamantane-2-carboxylic acid hydrochloride, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylaminopropyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl-methylcarbamoyl-2-propan-2-ylphenyl pyrazole-3-carbonyl amino adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-3-dimethylamino propyl methyl carbamoyl-2-isopropylphenyl pyrazole-3-amido adamantane-2-carboxylic acid, 2-5-2,6-dimethoxyphenyl-1-4-n-methyl-n-3-dimethylaminopropyl carbamoyl-2-isopropylphenyl-3-pyrazolylcarbonylamino-2-adamantanecarboxylic acid
CC(C)C1=C(C=CC(=C1)C(=O)N(C)CCCN(C)C)N2C(=CC(=N2)C(=O)NC3(C4CC5CC(C4)CC3C5)C(=O)O)C6=C(C=CC=C6OC)OC
685.866
685.86
SR 142948
C39H51N5O6
LWULHXVBLMWCHO-UHFFFAOYSA-N
2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methylcarbamoyl]-2-propan-2-ylphenyl]pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid
5311451
>97%
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