SPI-B Mouse anti-Human, Biotin, Clone: 235D, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-9790-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15587386

 N/A
N/A

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance


Description and Specification

Specification

Antigen SPI-B
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Isotype IgG1
Concentration 0.5mg/mL
Clone 235D
Gene Alias ETS
Species Reactivity Human
Format Conjugated
Quantity 25μg
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze.
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Host Species Mouse
Conjugate Biotin

The 235D monoclonal antibody recognizes human SPI-B. SPI-B is a member of the ETS transcription factor family which is comprised of DNA binding proteins that function in lymphoid development and activity. SPI-B binds the PU box, a purine-rich DNA sequence (5’-GAGGAA-3’). SPI-B is expressed in mature B cells, immature T cells, plasmacytoid dendritic cells, and microfold cells (M cells) of the intestine. In human tonsil tissue, high levels of SPI-B are expressed in plasmacytoid dendritic cells, while lower levels of expression are found in germinal center B cells.