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SP 600125, Tocris Bioscience™

Selective JNK inhibitor

Brand:  Tocris (Bio-Techne) 149650

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13439433

  • £347.17 / 50mg

Estimated Shipment
09-07-2019

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Description

Description

Selective JNK inhibitor. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes. Active in vivo. Exhibits reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis. Prevents BMP9-induced osteogenic differentiation of MSCs. Essential component of medium for maintaining stem cells in naive pluripotent state. Available as part of the MAPK Inhibitor Tocriset™ .
Specifications

Chemical Identifiers

129-56-6
220.231
1,9-pyrazoloanthrone, pyrazolanthrone, dibenzo cd,g indazol-6 2h-one, pyrazoleanthrone, anthra 1,9-cd pyrazol-6 2h-one, anthra-1,9-pyrazol-6-none, 2h-dibenzo cd,g indazol-6-one, jnk inhibitor ii, sapk inhibitor ii, anthra 1,9-cd pyrazol-6 2h-one
C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
C14H8N2O
ACPOUJIDANTYHO-UHFFFAOYSA-N
8515

Specifications

SP 600125
129-56-6
1,9-pyrazoloanthrone, pyrazolanthrone, dibenzo cd,g indazol-6 2h-one, pyrazoleanthrone, anthra 1,9-cd pyrazol-6 2h-one, anthra-1,9-pyrazol-6-none, 2h-dibenzo cd,g indazol-6-one, jnk inhibitor ii, sapk inhibitor ii, anthra 1,9-cd pyrazol-6 2h-one
C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
8515
>98%
50mg
C14H8N2O
ACPOUJIDANTYHO-UHFFFAOYSA-N
220.231
220.23
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