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SOX9 Monoclonal Antibody (GMPR9), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9765-80

Code : NEW

Additional Details : Weight : 0.09500kg

Product Code. 15550287

  • £165.00 / 25µg
Estimated Shipment: 20-05-2024
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Description

Description

SOX9 has a role in sex determination and differentiation of Sertoli cells. It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Translocation of this gene can cause campomelic dysplasia. SOX9 is involved in the formation of testes from the indifferent fetal gonads. It is a major molecular component of the neuron-glia switch in developing spinal cord. During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium. These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion. SOX9 may direct the formation of neural crest precursors and the development of a range of neural crest derivative. It has a transcriptional regulation in melanin production in cells. Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.

SOX9 Monoclonal antibody specifically detects SOX9 in Human, Mouse samples. It is validated for Immunocytochemistry, Immunohistochemistry (Paraffin).
Specifications

Specifications

SOX9
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P48436, Q04887
SOX9
Affinity chromatography
RUO
20682, 6662
4° C, store in dark, DO NOT FREEZE!
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin)
GMPR9
Alexa Fluor 488
SOX9
2010306G03Rik; AV220920; CMD1; CMPD1; mKIAA4243; SOX 9; Sox9; SOX-9; Sox9 transcription factor; SRA1; SRXX2; SRXY10; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY box 9; SRY-box 9; SRY-Box 9 ; SRY-box containing 9; SRY-box containing gene 9; SRY-box containing protein 9; SRY-box transcription factor 9; SRY-related HMG-box, gene 9; transcription activator Sox9; transcription factor SOX-9
Mouse
25 μg
Primary
Human, Mouse
Antibody
IgG1 κ
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