Sox11 Mouse anti-Human, eFluor 660, Clone: SOX11-C1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9773-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15590127

Quantity Price
1 £ 198.54 / 100µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Format Conjugated
Host Species Mouse
Conjugate eFluor 660
Monoclonal or Polyclonal Monoclonal
Clone SOX11-C1
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Concentration 0.2mg/mL
Regulatory Status RUO
Species Reactivity Human
Isotype IgG1
Quantity 100μg
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen Sox11
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary

The monoclonal antibody SOX11-C1 (C1) recognizes human Sox11. The transcription factor Sox11 is a member of the SOX (sex determining region Y-related HMG (High Mobility Group) Box) family of proteins. Under normal conditions Sox11 is expressed in the developing central nervous system during embryogenesis and has sequence homology to Sox4. Sox11 plays a role in neuronal maturation and epithelial-mesenchymal interactions and is required for the survival of neuronal and mesenchymal progenitor cells. Sox11 is expressed in mantle cell lymphoma (MCL) and in subsets of hairy cell leukemias, Burkitt lymphomas, and B cell lymphoblastic leukemias, but is not expressed in other B cell lymphomas or in normal B lymphocytes. Sox11 is also expressed in epithelial ovarian cancer and gliomas.