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SOX11, clone: SOX11-C1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9773-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15507676

  • £75.77 / 25µg


EU Stock 1
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Description

Description

Description: The monoclonal antibody SOX11-C1 (C1) recognizes human Sox11. The transcription factor Sox11 is a member of the SOX (sex determining region Y-related HMG (High Mobility Group) Box) family of proteins. Under normal conditions Sox11 is expressed in the developing central nervous system during embryogenesis and has sequence homology to Sox4. Sox11 plays a role in neuronal maturation and epithelial-mesenchymal interactions and is required for the survival of neuronal and mesenchymal progenitor cells. Sox11 is expressed in mantle cell lymphoma (MCL) and in subsets of hairy cell leukemias, Burkitt lymphomas, and B cell lymphoblastic leukemias, but is not expressed in other B cell lymphomas or in normal B lymphocytes. Sox11 is also expressed in epithelial ovarian cancer and gliomas.Applications Reported: This SOX11-C1 antibody has been reported for use in flow cytometric analysis, western blotting, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, and immunocytochemistry.Applications Tested: This SOX11-C1 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using low or high pH antigen retrieval. The antibody can be used at less than or equal to 5 μg/mL. This SOX11-C1 antibody has been tested by immunocytochemistry of fixed and permeabilized cells and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Sox11
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P35716
SRY (sex-determining region Y)-box 11, SRY-related HMG-box gene 11, transcription factor SOX-11
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
SOX11-C1
Unconjugated
SOX11
Purified
SOX11
IgG1, kappa
25μg
Store at 2-8°C.
Primary
6664
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