missing translation for 'onlineSavingsMsg'
Learn More

Snail Mouse anti-Human, Alexa Fluor 488, Clone: 20C8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9859-82

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15560307

  • £161.27 / 100µg


Estimated Shipment date
from Supplier 24-11-2017
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody 20C8 recognizes human Snail1, a 29kDa zinc finger transcription factor. Snail1 and Slug both belong to a family of transcription factors that are responsible for inducing epithelial to mesenchymal transition (EMT) during normal organ development and tumor progression. Snail1 expression is localized to both the cytoplasm and nucleus and functions as a transcriptional repressor of E-cadherin, claudins, occludin, and desmoplakin. During embryonic development, Snail1 is localized to the mesoderm, while in the adult, expression is inducible and is usually limited to activated fibroblasts and some mesenchymal cells. Overexpression of Snail1 has been found in carcinomas and fibrosarcomas and may be used as an early marker for EMT.
Specifications

Specifications

Snail
20C8
Alexa Fluor 488
Conjugated
IgG2a
RUO
Primary
Human
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal