Snail1 Mouse anti-Human, Alexa Fluor® 488, Clone: 20C8, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 53-9859-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionExcitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered. Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Zinc finger protein SNAI1, Snail protein homolog, Sna protein|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Alexa Fluor™ 488|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.