SAP (SLAM-Associated Protein) Monoclonal Antibody (XLP-1D12), eFluor™ 660, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Product Code	Brand	Quantity
15570137	Affymetrix eBioscience 50-9787-42	100 Tests
15560137	Affymetrix eBioscience 50-9787-41	25 Tests

Description

This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.

SAP (SLAM-Associated Protein) Monoclonal antibody specifically detects SAP (SLAM-Associated Protein) in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: SAP (SLAM-Associated Protein)
• Applications: Flow Cytometry
• Conjugate: eFluor 660
• Host Species: Rat
• Target Species: Human
• Gene ID (Entrez): 4068
• Primary or Secondary: Primary
• Product Type: Antibody

• Clone: XLP-1D12
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Gene Accession No.: O60880
• Isotype: IgG2a κ
• Purification Method: Affinity chromatography

For Research Use Only.