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SKF 89976A hydrochloride, Tocris™

Potent GABA uptake inhibitor. Penetrates blood brain barrier

Brand:  Tocris (Bio-Techne) 108110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13488513

  • £132.00 / 10mg


Estimated Shipment
03-11-2017
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Description

Description

A potent GABA uptake inhibitor, selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo.
Specifications

Chemical Identifiers

SKF 89976A hydrochloride
C22H25NO2·HCl
1-(4, 4-Diphenyl-3-butenyl)-3-piperidinecarboxylic acid hydrochloride
>99%
371.91

Specifications

SKF 89976A hydrochloride
>99%
371.91
10mg
85375-15-1
C22H25NO2·HCl
1-(4, 4-Diphenyl-3-butenyl)-3-piperidinecarboxylic acid hydrochloride