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SKF 83822 hydrobromide, Tocris Bioscience™

Selective D1-like agonist

Brand:  Tocris (Bio-Techne) 207510

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13440424

  • £170.28 / 10mg

Estimated Shipment date
from Supplier 24-09-2019

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Description

Description

High affinity, selective dopamine D1-like receptor agonist. Ki values are 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, α1A and α1B receptors respectively. Stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal and hyperlocomotion following subcutaneous administration in monkeys.
Specifications

Chemical Identifiers

74115-10-9
424.763
skf 83822 hydrobromide, skf-83822 hydrobromide, 6-chloro-2,3,4,5-tetrahydro-1-3-methylphenyl-3-2-propenyl-1h-3-benzazepine-7,8-diol hydrobromide, n-allyl-6-chloro-1-3-methylphenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide, 3-allyl-6-chloro-1-3-methylphenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol hydrobromide, 3-allyl-6-chloro-7,8-dihydroxy-1-3-methylphenyl-2,3,4,5-tetrahydro-1h-3-benzazepinium bromide, 6-chloro-1-3-methylphenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol hydrobromide, 6-chloro-7,8-dihydroxy-1-3-methylphenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1h-3-benzazepinium bromide, skf83822 hydrobromide, 1h-3-benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-3-methylphenyl-3-2-propen-1-yl-, hydrobromide 1:1
CHEBI:64002
CC1=CC=CC(=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)CC=C.Br
C20H23BrClNO2
CFWPKYBBXBANLU-UHFFFAOYSA-N
12909789
9-chloro-5-(3-methylphenyl)-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol;hydrobromide

Specifications

SKF 83822 hydrobromide
74115-10-9
skf 83822 hydrobromide, skf-83822 hydrobromide, 6-chloro-2,3,4,5-tetrahydro-1-3-methylphenyl-3-2-propenyl-1h-3-benzazepine-7,8-diol hydrobromide, n-allyl-6-chloro-1-3-methylphenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide, 3-allyl-6-chloro-1-3-methylphenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol hydrobromide, 3-allyl-6-chloro-7,8-dihydroxy-1-3-methylphenyl-2,3,4,5-tetrahydro-1h-3-benzazepinium bromide, 6-chloro-1-3-methylphenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol hydrobromide, 6-chloro-7,8-dihydroxy-1-3-methylphenyl-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1h-3-benzazepinium bromide, skf83822 hydrobromide, 1h-3-benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-3-methylphenyl-3-2-propen-1-yl-, hydrobromide 1:1
CC1=CC=CC(=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)CC=C.Br
424.763
CHEBI:64002
>98%
10mg
C20H23BrClNO2
CFWPKYBBXBANLU-UHFFFAOYSA-N
9-chloro-5-(3-methylphenyl)-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol;hydrobromide
12909789
424.76
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