Sino Biological™ TGFBR2, Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Asp 159) of human TGFβ receptor 2 (NP_003233.4) fused to the fused C-terminal His-tagged Fc region of human IgG1 at the C-terminus

Overview
Brand: Invitrogen

Manufacturer Part Number: 10358H03H25

UNSPSC: 12352202

Code: NEW

Additional Details:
Additional Details: Weight: 0.10000kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 15245265

Quantity Price
1 £ 230.0 / 25µg
Estimated Shipment date
from Supplier 06-04-2017
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Description and Specification

Specification

Gene ID (Entrez) 7048
Validated Application Assay Standard
Common Name Transforming growth factor, beta receptor II
Expression System Mammalian
For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Purity ≥85% by SDS-PAGE
Molecular Weight 43.4kDa
Quantity 5 x 5μg
Storage Requirements Store at -5° to -30°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Purification Method PAGE
Structural Form Truncated/Recombinant
Gene Symbol TGFBR2
Endotoxin Concentration <1 EU/μg
Gene Alias AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII, TGFBR2
Protein Family Growth Factors & Receptors
Protein Tag hIgG1-Fc His

Transforming Growth Factor, Beta Receptor II (TGFBR2), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.
  • Activity: Measured by its ability to inhibit TGF-beta1 activity on Mv-1-lu mink lung epithelial cells, the ED50 for this effect is typically 1-3μg/mL in the presence of 1ng/mL of recombinant human TGF-beta1
  • Formulation: 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

This protein is manufactured by Sino Biological Inc.