Sino Biological™ IL6ST Recombinant Mouse Protein, hIgG1-Fc.His Tag, CHO expressed

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 617) of mouse IL6ST (NP_034690.3) fused to the polyhistidine-tagged Fc region of human IgG1 at the C-terminus

Overview
Brand: Invitrogen

Manufacturer Part Number: 50135M03C25

IL6ST Recombinant Mouse Protein (hIgG1-Fc.His Tag,

UNSPSC: 12352202

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 13496226

Quantity Price
1 £ 139.0 / 25µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Format Lyophilized
Gene ID (Entrez) 16195
Molecular Weight 94.7kDa
Purity ≥90% by SDS-PAGE
Quantity 5 x 5μg
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant
Protein Subtype Interleukins|Cytokine Receptors
Endotoxin Concentration <1 EU/μg
Gene Alias IL6ST, 5133400A03Rik, AA389424, BB405851, CD130, gp130
Common Name Interleukin 6 signal transducer
Gene Symbol IL6ST
Protein Tag His Tag/IgG1 Fc Tag
Validated Application Assay Standard
Protein Family Cytokines & Receptors/CD Proteins
Expression System Mammalian

Interleukin 6 signal transducer (IL6ST), recombinant mouse protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.
  • Activity: Measured by its ability to inhibit the IL6R enhancement of IL6 activity on M1 mouse myeloid leukemia cells (Saito, T. et al. 1991, J. Immunol. 147:168); the ED50 for this effect is typically 0.03-0.1μg/mL in the presence of 50ng/mL recombinant human IL6R and 100ng/mL recombinant human IL6
  • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.