Sino Biological™ IgG1-Fc Recombinant Human Protein

This recombinant human protein is expressed from a DNA sequence encoding the human IgG1-Fc region (AAC82527.1), containing residues 99 to 330, including a 103 Cys/Ser mutation

Overview
Brand: Invitrogen

Manufacturer Part Number: 10702HNAH250

IgG1-Fc Recombinant Human Protein (Native), 250 µg

UNSPSC: 12352202

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 13435946

Quantity Price
1 £ 264.0 / 250µg
EU Stock 1
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Description and Specification

Specification

Quantity 5 x 50μg
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Endotoxin Concentration <1 EU/μg
Gene Symbol IgG1-Fc
Molecular Weight 26kDa
Purity ≥95% by SDS-PAGE
Structural Form Truncated/Recombinant
Protein Subtype Other Proteins
Gene Alias Fc region of human immunoglobulin G1
Common Name Fc region of human immunoglobulin G1
Protein Tag IgG1 Fc Tag
Validated Application Assay Standard
Protein Family Growth Factors & Receptors
Expression System Mammalian
For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Cell Analysis; Immunoassays; Protein Assay Controls, Reference Standards & Accessories; Build-Your-Own Immunoassay
Format Lyophilized

Immunoglobulin gamma-1 heavy chain constant region, partial (IgG1-Fc), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.&line-break;Background: Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). Recombinant IgG Fc is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.
  • N-terminal Sequence Analysis: Glu 99
  • Activity: 1. Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H1) in a functional ELISA; 2. Measured by its ability to bind human CD16a-AVI-His (Mfr. No. 10389-H27H) in a functional ELISA; 3.Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H) in a functional ELISA
  • Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80
  • Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature