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IgG1-Fc Recombinant Human Protein, Invitrogen™ Sino Biological™
This recombinant human protein is expressed from a DNA sequence encoding the human IgG1-Fc region (AAC82527.1), containing residues 99 to 330, including a 103 Cys/Ser mutation
Brand: Invitrogen 10702HNAH25
Code : NEW
Additional Details : Weight : 0.01000kg
Description
Immunoglobulin gamma-1 heavy chain constant region, partial (IgG1-Fc), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.&line-break;Background: Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). Recombinant IgG Fc is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.- N-terminal Sequence Analysis: Glu 99
- Activity: 1. Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H1) in a functional ELISA; 2. Measured by its ability to bind human CD16a-AVI-His (Mfr. No. 10389-H27H) in a functional ELISA; 3.Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H) in a functional ELISA
- Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween™-80
- Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible
Shipping Condition: Room Temperature. Manufactured by Sino Biological (China).
Specifications
Protein Expression and Isolation, Enzyme and Protein Activity Assay, Protein Assay Control, Reference Standards and Accessories | |
5 x 5μg | |
Truncated/Recombinant | |
Fc region of human immunoglobulin G1 | |
IgG1-Fc | |
Mammalian | |
Lyophilized | |
≥95% by SDS-PAGE |
26kDa | |
Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed. | |
<1 EU/μg | |
Fc region of human immunoglobulin G1 | |
IgG1 Fc Tag | |
Growth Factors & Receptors | |
Other Proteins |
For Research Use Only. Not for use in diagnostic procedures.