Sino Biological™ FGFR4, Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Asp 369) of human FGFR4 (NP_002002.3) precursor fused to the C-terminal polyhistidine tagged Fc region of human IgG1 at the C-terminus

Overview
Brand: Invitrogen

Manufacturer Part Number: 10538H03H50

FGFR4, RECOMBINANT HUMAN PROTEIN (WITHOUT CATALYTI

UNSPSC: 12352202

Code: NEW

Additional Details:
Additional Details: Weight: 0.10000kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 15276895

Quantity Price
1 £ 210.0 / 50µg
Estimated Shipment date
from Supplier 12-12-2016
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Description and Specification

Specification

For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Gene ID (Entrez) 2264
Molecular Weight 66kDa
Purification Method PAGE
Purity ≥85% by SDS-PAGE
Quantity 50μg
Storage Requirements Store at -5° to -30°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant
Endotoxin Concentration <1 EU/μg
Gene Alias FGFR4, CD334, JTK2, mgC20292, TKF
Common Name fibroblast growth factor receptor 4
Gene Symbol FGFR4
Protein Tag hIgG1-Fc His
Validated Application Assay Standard
Protein Family Cytokines & Receptors
Expression System Mammalian

Fibroblast Growth Factor Receptor 4 (FGFR4), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.
  • Activity: Measured by its ability to inhibit FGF acidic dependent proliferation of Balb3T3 mouse fibroblasts, the ED50 for this effect is typically 2-6ng/mL
  • Formulation: 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

This protein is manufactured by Sino Biological Inc.