Sino Biological™ FGFR2 Recombinant Human Protein (without Catalytic Activity Domain), His Tag

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 377) of human FGFR2 (NP_000132.3) fused to a polyhistidine tag at the C-terminus

Overview
Brand: Invitrogen

Manufacturer Part Number: 10824H08H25

UNSPSC: 12352202

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 13445976

Quantity Price
1 £ 139.0 / 25µg
Estimated Shipment date
from Supplier 13-04-2017
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Description and Specification

Specification

For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Gene Symbol FGFR2
Validated Application Assay Standard
Common Name Fibroblast growth factor receptor 2
Protein Tag His Tag
Format Lyophilized
Purity ≥85% by SDS-PAGE
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Protein Family Growth Factors & Receptors
Structural Form Truncated/Recombinant
Protein Subtype Receptor Tyrosine Kinases|Growth Factor Receptors
Gene ID (Entrez) 2263
KinaseFamily FGF Receptor Kinase Family
Quantity 5 x 5μg
Molecular Weight 41kDa
Gene Alias BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FLJ98662, JWS, K-SAM, KGFR, TK14, TK25
Expression System Mammalian
Endotoxin Concentration <1 EU/μg

Fibroblast growth factor receptor 2 (FGFR2), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in cell-based assays, protein structure analysis, as immunogen, protein standard, and other research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.
  • Activity: Measured by its ability to inhibit FGF1-dependent proliferation of Balb/c 3T3 mouse embryonic fibroblasts, the ED50 for this effect is typically 200-400ng/mL
  • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.