Sino Biological™ FGFR1 Recombinant Mouse Protein (without Catalytic Activity Domain), hIgG1-Fc Tag

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 376) of mouse FGFR1 isoform 1 (P16092-1) fused to the Fc region of human IgG1 at the C-terminus

Overview
Brand: Invitrogen

Manufacturer Part Number: 50186M02H5

UNSPSC: 12352202

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 13436246

Quantity Price
1 £ 80.5 / 5µg
Estimated Shipment date
from Supplier 10-04-2017
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Description and Specification

Specification

Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Quantity 5μg
Protein Subtype Receptor Tyrosine Kinases|Growth Factor Receptors
Validated Application Assay Standard
For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Format Lyophilized
Endotoxin Concentration <1 EU/μg
Common Name Fibroblast growth factor receptor 1
Expression System Mammalian
Protein Tag IgG1 Fc Tag
KinaseFamily FGF Receptor Kinase Family
Gene ID (Entrez) 14182
Gene Alias AW208770, FLG, Fgfr-1, Flt-2
Molecular Weight 66.5kDa
Protein Family Growth Factors & Receptors
Purity ≥85% by SDS-PAGE
Gene Symbol FGFR1
Structural Form Truncated/Recombinant

Fibroblast growth factor receptor 1 (FGFR1), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.
  • Activity: Measured by its ability to inhibit FGF1-dependent proliferation of BABL/c 3T3 mouse embryonic fibroblasts; the ED50 for this effect is typically 0.1-0.6ng/mL
  • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.