FGFR1 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag, Invitrogen™ Sino Biological™

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 285) of human FGFR1 (NP_075594.1) fused to the polyhistidine-tagged Fc region of human IgG1 at the C-terminus

Brand:  Invitrogen 10616H03H25

Product Code. 13445916

Description

Fibroblast growth factor receptor 1 (FGFR1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

• Activity: Measured by its ability to inhibit FGF1-dependent proliferation of BALB/c 3T3 mouse fibroblasts, the ED₅₀ for this effect is typically 2-4ng/mL
• Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80
• Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.

Specifications

• For Use With (Application): Protein Expression and Isolation, Enzyme and Protein Activity Assay, Protein Assay Control, Reference Standards and Accessories
• Molecular Weight (g/mol): 57.5kDa
• Storage Requirements: Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
• Endotoxin Concentration: <1 EU/μg
• Common Name: Fibroblast growth factor receptor 1
• KinaseFamily: FGF Receptor Kinase Family
• Expression System: Mammalian
• Form: Lyophilized
• Purity or Quality Grade: ≥85% by SDS-PAGE

• Gene ID (Entrez): 2260
• Quantity: 5 x 5μg
• Structural Form: Truncated/Recombinant
• Gene Alias: FGFR1, BFGFR, CD331, CEK, FGFBR, FLG, FLJ99988, FLT2, HBGFR, KAL2, N-SAM
• Gene Symbol: FGFR1
• Protein Tag: His Tag/IgG1 Fc Tag
• Protein Family: Growth Factors & Receptors
• Protein Subtype: Receptor Tyrosine Kinases, Growth Factor Receptors

For Research Use Only. Not for use in diagnostic procedures.