ERBB2 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc Tag, Invitrogen™ Sino Biological™
This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Thr 652) of human ERBB2 (NP_004439.2) fused to the Fc region of human IgG1 at the C-terminus
Brand: Invitrogen 10004H02H5
Code : NEW
Additional Details : Weight : 0.01000kg
DescriptionV-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins are suitable for use in studying protein-protein interactions, as a protein standard, or in cell biology research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.
- Activity: Measured by its binding ability in a functional ELISA; immobilized human ERBB2 at 2.5μg/mL can bind Herceptin with a linear range of 3.2-80ng/mL
- Formulation: Lyophilized in 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween-80
- Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible
This protein is manufactured by Sino Biological Inc.
|Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories|
|Truncated/Recombinant/Cell Surface Protein|
|v-erb-b2 erythroblastic leukemia viral oncogene homolog 2|
|IgG1 Fc Tag|
|≥85% by SDS-PAGE|
|Store at -20°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.|
|Receptor Tyrosine Kinases|Growth Factor Receptors|
|ErbB2, NEU, NGL, HER2, TKR1, CD340, HER-2, c-erb B2, HER-2/neu|
|Growth Factors & Receptors|
|EGF Receptor (ErbB) Kinase Family|
For Research Use Only. Not for use in diagnostic procedures.