Sino Biological™ BMPR1A, Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Arg 152) of human ALK3 (NP_004320.2) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus

Overview
Brand: Invitrogen

Manufacturer Part Number: 10446H03H50

UNSPSC: 12352202

Code: NEW

Additional Details:
Additional Details: Weight: 0.10000kg



Disclaimers: For Research Use Only. Not for use in diagnostic procedures.

Product Code. 15255435

Quantity Price
1 £ 155.0 / 50µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Gene ID (Entrez) 657
Molecular Weight 42kDa
Purity ≥85% by SDS-PAGE
Purification Method PAGE
Endotoxin Concentration <1 EU/μg
Gene Symbol BMPR1A
Validated Application Assay Standard
Common Name Bone morphogenetic protein receptor, type IA
Protein Tag hIgG1-Fc His
Protein Family Growth Factors & Receptors
Storage Requirements Store at -5° to -30°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Gene Alias ACVRLK3, ALK3, CD292, BMPR1A
Quantity 50μg
Expression System Mammalian
For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Structural Form Truncated/Recombinant

Bone Morphogenetic Protein Receptor, Type IA (BMPR1A), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.
  • Activity: Measured by its ability to inhibit BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells, the ED50 for this effect is typically 0.1-0.3μg/mL in the presence of 50ng/mL of recombinant human BMP4
  • Formulation: 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

This protein is manufactured by Sino Biological Inc.