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Tocris Bioscience™ SIB 1893

mGlu5 antagonist; also positive allosteric modulator at mGlu4 receptors

Brand:  Tocris Bioscience™ 121450

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13448903

  • £521.85 / 50mg

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Description

Description

A highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.
Specifications

Specifications

SIB 1893
SIB 1893
195.26
50mg
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