Semaphorin 4A Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: 5E3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9753-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15529436

Quantity Price
1 £ 201.16 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Isotype IgG1
Primary or Secondary Primary
Applications Flow Cytometry
Regulatory Status RUO
Format Conjugated
Concentration 5μL (0.06μg)/test
Species Reactivity Human, Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Gene Alias Sema B, Sema4A
Monoclonal or Polyclonal Monoclonal
Antigen Semaphorin 4A
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100 tests
Clone 5.00E+03
Conjugate PerCP-eFluor 710
Host Species Mouse

The monoclonal antibody 5E3 reacts with human and mouse Semaphorin 4A (Sema4A). This 150kDa glycoprotein is a member of the class IV semaphorin family and exists as membrane-bound and soluble forms. Sema4A is expressed by a wide variety of tissues, including lung, kidney, spleen, testis, and mammary glands, as well as activated T cells and dendritic cells. This ligand binds to Tim-2, neuropilin-1 (Nrp1), plexin D1, and plexin B1. Sema4A plays a role in T cell activation, Th1 differentiation, and Treg function and survival.

Our testing demonstrates that the 5E3 antibody stains resting CD49b+ NK cells in mouse. However, staining of CD56+ NK cells in human is negative.