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Semaphorin 4A Mouse anti-Human, Mouse, APC, Clone: 5E3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-9753-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15568256

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody 5E3 reacts with human and mouse Semaphorin 4A (Sema4A). This 150kDa glycoprotein is a member of the class IV semaphorin family and exists as membrane-bound and soluble forms. Sema4A is expressed by a wide variety of tissues, including lung, kidney, spleen, testis, and mammary glands, as well as activated T cells and dendritic cells. This ligand binds to Tim-2, neuropilin-1 (Nrp1), plexin D1, and plexin B1. Sema4A plays a role in T cell activation, Th1 differentiation, and Treg function and survival.

Our testing demonstrates that the 5E3 antibody stains resting CD49b+ NK cells in mouse. However, staining of CD56+ NK cells in human is negative.
Specifications

Specifications

Semaphorin 4A
5.00E+03
Allophycocyanin
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Sema B, Sema4A
IgG1
RUO
Primary
Murine