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Tocris Bioscience™ SB 525334

Selective inhibitor of TGF-βRI

POA

Specifications

Product Type SB 525334
Inhibitors SB 525334
Molecular Weight 343.42
Purity >97
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Description

Description

Selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM). Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells. Attenuates bleomycin-induced pulmonary fibrosis.
Specifications

Specifications

SB 525334
SB 525334
343.42
>97

For Research Use Only