SB 222200, Tocris Bioscience™

Potent, selective non-peptide NK3 antagonist. Brain penetrant

Brand:  Tocris (Bio-Techne) 1393/10

Product Code. 13459293

Description

Potent and selective non-peptide NK3 receptor antagonist (Ki values are 4.4, > 100,000 and 250 nM for human NK3, NK1 and NK2 receptors respectively). Antihypertensive in vivo. Brain penetrant.

Chemical Identifiers

• CAS: 174635-69-9
• Molecular Weight (g/mol): 380.491
• Synonym: 3-methyl-2-phenyl-n-1s-1-phenylpropyl quinoline-4-carboxamide, chembl10284, s-3-methyl-2-phenyl-n-1-phenylpropyl-4-quinolinecarboxamide, 3-methyl-2-phenyl-n-1s-1-phenylpropyl-4-quinolinecarboxamide, s-3-methyl-2-phenyl-n-1-phenylpropyl quinoline-4-carboxamide, 4-quinolinecarboxamide, 3-methyl-2-phenyl-n-1s-1-phenylpropyl, 4-quinolinecarboxamide, 3-methyl-2-phenyl-n-1s-1-phenylpropyl, tocris-1393, lopac-s-5192, d00vpt
• IUPAC Name: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide

• Molecular Formula: C26H24N2O
• InChI Key: MQNYRKWJSMQECI-QFIPXVFZSA-N
• PubChem CID: 6604009
• SMILES: CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)C

Specifications

• Chemical Name or Material: SB 222200
• CAS: 174635-69-9
• Synonym: 3-methyl-2-phenyl-n-1s-1-phenylpropyl quinoline-4-carboxamide, chembl10284, s-3-methyl-2-phenyl-n-1-phenylpropyl-4-quinolinecarboxamide, 3-methyl-2-phenyl-n-1s-1-phenylpropyl-4-quinolinecarboxamide, s-3-methyl-2-phenyl-n-1-phenylpropyl quinoline-4-carboxamide, 4-quinolinecarboxamide, 3-methyl-2-phenyl-n-1s-1-phenylpropyl, 4-quinolinecarboxamide, 3-methyl-2-phenyl-n-1s-1-phenylpropyl, tocris-1393, lopac-s-5192, d00vpt
• SMILES: CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)C
• Molecular Weight (g/mol): 380.491
• Formula Weight: 380.48

• Quantity: 10mg
• Molecular Formula: C26H24N2O
• InChI Key: MQNYRKWJSMQECI-QFIPXVFZSA-N
• IUPAC Name: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
• PubChem CID: 6604009
• Percent Purity: >98%