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SB 218795, Tocris Bioscience™

Potent, selective non-peptide NK3 antagonist

Brand:  Tocris (Bio-Techne) 1376/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13459253

  • £183.48 / 10mg


Estimated Shipment
29-11-2018
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Description

Description

Potent, selective and competitive non-peptide NK3 receptor antagonist (Ki = 13 nM at hNK3). Displays 90-fold and 7000-fold selectivity over hNK2 and hNK1 receptors respectively. Active in vivo, inhibiting agonist-induced pupillary constriction.
Specifications

Chemical Identifiers

174635-53-1
396.446
chembl9843, --r-n-alpha-methoxycarbonylbenzyl-2-phenylquinoline-4-carboxamide, methyl 2r-2-phenyl-2-2-phenylquinoline-4-carbonyl amino acetate, tocris-1376, nk-3 antagonists, sb, nk-2 antagonists, gsk, d02cca, nk-3 antagonists, glaxosmithkline, methyl 2r-phenyl 2-phenyl-4-quinolinyl carbonyl amino acetate, --r-n-, a-methoxycarbonylbenzyl-2-phenylquinoline-4-carboxamide
methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate
C25H20N2O3
IUMQXQJZIHWLIN-HSZRJFAPSA-N
6604858
COC(=O)C(C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4

Specifications

SB 218795
174635-53-1
chembl9843, --r-n-alpha-methoxycarbonylbenzyl-2-phenylquinoline-4-carboxamide, methyl 2r-2-phenyl-2-2-phenylquinoline-4-carbonyl amino acetate, tocris-1376, nk-3 antagonists, sb, nk-2 antagonists, gsk, d02cca, nk-3 antagonists, glaxosmithkline, methyl 2r-phenyl 2-phenyl-4-quinolinyl carbonyl amino acetate, --r-n-, a-methoxycarbonylbenzyl-2-phenylquinoline-4-carboxamide
COC(=O)C(C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
396.446
396.44
10mg
C25H20N2O3
IUMQXQJZIHWLIN-HSZRJFAPSA-N
methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate
6604858
>99%
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