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SB 202190, Tocris Bioscience™

Potent, selective inhibitor of p38 MAPK

Brand:  Tocris (Bio-Techne) 126410

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13459013

  • £165.00 / 10mg


Estimated Shipment
27-11-2018
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Description

Description

A highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. Binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms (IC50 = 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2 respectively). Promotes stability of naive human pluripotent stem cells in culture. Also available as part of the MAPK Inhibitor Tocriset™ .
Specifications

Chemical Identifiers

152121-30-7
331.35
fhpi, unii-pvx798p8gi, 4-4-fluorophenyl-2-4-hydroxyphenyl-5-4-pyridyl imidazole, 4-4-fluorophenyl-2-4-hydroxyphenyl-5-4-pyridyl-1h-imidazole, pvx798p8gi, sb 202190, immobilized, insolution sb 202190, 4-4-4-fluorophenyl-5-pyridin-4-yl-1h-imidazol-2-yl phenol, phenol, 4-4-4-fluorophenyl-5-4-pyridinyl-1h-imidazol-2-yl, 4-4-4-fluorophenyl-5-pyridin-4-yl-1h-imidazol-2-yl phenol
4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one
C20H14FN3O
NJNKPVPFGLGHPA-UHFFFAOYSA-N
5353940
C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F

Specifications

SB 202190
152121-30-7
fhpi, unii-pvx798p8gi, 4-4-fluorophenyl-2-4-hydroxyphenyl-5-4-pyridyl imidazole, 4-4-fluorophenyl-2-4-hydroxyphenyl-5-4-pyridyl-1h-imidazole, pvx798p8gi, sb 202190, immobilized, insolution sb 202190, 4-4-4-fluorophenyl-5-pyridin-4-yl-1h-imidazol-2-yl phenol, phenol, 4-4-4-fluorophenyl-5-4-pyridinyl-1h-imidazol-2-yl, 4-4-4-fluorophenyl-5-pyridin-4-yl-1h-imidazol-2-yl phenol
C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
331.35
331.35
10mg
C20H14FN3O
NJNKPVPFGLGHPA-UHFFFAOYSA-N
4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one
5353940
>99%
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