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S100A8 Mouse anti-Human, eFluor 660, Clone: CF-145, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9745-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15500117

  • £72.77 / 25 tests


Estimated Shipment date
from Supplier 29-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody CF-145 recognizes human S100A8. S100A8, also known as migration inhibitory factor-related protein 8 (MRP-8) or Calgranulin-A, is a calcium binding protein and member of the S100 family of proteins. S100A8 is expressed by neutrophils, monocytes, macrophages, granulocytes, and epithelial cells during dermatoses, such as psoriasis. S100A8 forms a heterodimer with S100A9, which together is known as calprotectin. S100A8 has antimicrobial and pro-apoptotic properties and is a pro-inflammatory mediator in acute and chronic inflammation. Levels of S100A8 are elevated in patients with various inflammatory disorders such as cystic fibrosis, rheumatoid arthritis, and chronic bronchitis. Upregulation of S100A8 is also observed in many tumors, including skin, breast, colon, pancreatic, and ovarian cancers.
Description & Specifications

Specifications

S100A8
CF-145
eFluor 660
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.06μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Calgranulin A, Calprotectin
IgG2b
RUO
Primary
Human