S100A8 Mouse anti-Human, Clone: CF-145, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9745-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15537626

Quantity Price
1 £ 142.93 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Conjugate Unlabeled
Format Purified
Gene Alias Calgranulin A, Calprotectin
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2b
Host Species Mouse
Species Reactivity Human
Primary or Secondary Primary
Storage Requirements Store at 2-8°C.
Clone CF-145
Quantity 100μg
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Concentration 0.5mg/mL
Antigen S100A8

The monoclonal antibody CF-145 recognizes human S100A8. S100A8, also known as migration inhibitory factor-related protein 8 (MRP-8) or Calgranulin-A, is a calcium binding protein and member of the S100 family of proteins. S100A8 is expressed by neutrophils, monocytes, macrophages, granulocytes, and epithelial cells during dermatoses, such as psoriasis. S100A8 forms a heterodimer with S100A9, which together is known as calprotectin. S100A8 has antimicrobial and pro-apoptotic properties and is a pro-inflammatory mediator in acute and chronic inflammation. Levels of S100A8 are elevated in patients with various inflammatory disorders such as cystic fibrosis, rheumatoid arthritis, and chronic bronchitis. Upregulation of S100A8 is also observed in many tumors, including skin, breast, colon, pancreatic, and ovarian cancers.