(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%, Thermo Scientific Chemicals

Description

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

Solubility
Readily soluble in hexane, ether, THF, CH2Cl2, benzene.

Notes
Hygroscopic. Store under inert gas. Store away from oxidizing agents, moisture.

Specifications

• Melting Point: 43°C to 45°C
• Density: 1.344
• Boiling Point: 105°C to 107°C (1 mmHg)
• Flash Point: >110°C (230°F)
• Quantity: 500 mg
• Beilstein: 3591561
• Sensitivity: Hygroscopic
• Merck Index: 14,6280
• Solubility Information: Readily soluble in hexane,ether,THF,CH2Cl2,benzene.
• Optical Rotation: −72° (c=2 in Methanol)
• Formula Weight: 234.18
• Percent Purity: 99%
• Chemical Name or Material: (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

RUO – Research Use Only