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Runx3 Mouse anti-Human, eFluor 660, Clone: R3-5G4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9817-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15520147

  • £67.82 / 25µg


Estimated Shipment date
from Supplier 04-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This R3-5G4 monoclonal antibody recognizes human Runx3, a 44kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers).
Description & Specifications

Specifications

Runx3
R3-5G4
eFluor 660
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunohistochemistry
0.2mg/mL
Conjugated
AML2, CBFA3
IgG1
RUO
Primary
Human