Runx3 Mouse anti-Human, Clone: R3-5G4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9817-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15238187

Quantity Price
1 £ 133.91 / 100µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Isotype IgG1
Regulatory Status RUO
Quantity 100μg
Primary or Secondary Primary
Clone R3-5G4
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Format Purified
Conjugate Unlabeled
Gene Alias AML2, CBFA3
Host Species Mouse
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C.
Antigen Runx3

This R3-5G4 monoclonal antibody recognizes human Runx3, a 44kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers).