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RUNX3, Biotin, clone: R3-5G4, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-9817-80
Code : NEW
Additional Details : Weight : 0.09500kg
Description
This R3-5G4 monoclonal antibody recognizes human Runx3, a 44kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers).Specifications
Runx3 | |
R3-5G4 | |
Biotin | |
Conjugated | |
Murine | |
25μg | |
Store at 2-8°C. Do not freeze. | |
Monoclonal |
Western Blot | |
0.5mg/mL | |
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer | |
AML2, CBFA3 | |
IgG1, kappa | |
RUO | |
Primary | |
Human |
For Research Use Only.