RUNX3, Biotin, clone: R3-5G4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-9817-80

Product Code. 15507396

Description

This R3-5G4 monoclonal antibody recognizes human Runx3, a 44kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers).

Specifications

• Antigen: Runx3
• Clone: R3-5G4
• Conjugate: Biotin
• Format: Conjugated
• Host Species: Murine
• Quantity: 25μg
• Storage Requirements: Store at 2-8°C. Do not freeze.
• Monoclonal or Polyclonal: Monoclonal

• Applications: ImmunohistochemistryþWestern Blot
• Concentration: 0.5mg/mL
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Gene Alias: AML2, CBFA3
• Isotype: IgG1, kappa
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

For Research Use Only.