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Runx3 Mouse anti-Human, Biotin, Clone: R3-5G4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-9817-80

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15507396

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Description

Description

This R3-5G4 monoclonal antibody recognizes human Runx3, a 44kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers).
Specifications

Specifications

Runx3
R3-5G4
Biotin
Conjugated
Murine
25μg
Store at 2-8°C. Do not freeze.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
AML2, CBFA3
IgG1
RUO
Primary
Human