RUNX3, Biotin, clone: R3-5G4, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-9817-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: This R3-5G4 monoclonal antibody recognizes human Runx3, a 44kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers).Applications Reported: This R3-5G4 antibody has been reported for use in western blotting, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This R3-5G4 antibody has been tested by immunohistochemistry on human FFPE tissue sections using high pH antigen retrieval at less than or equal to 20 ug/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.