RS 127445 hydrochloride, Tocris Bioscience™

Selective, high affinity 5-HT2B antagonist

Brand:  Tocris (Bio-Techne) 2993/10

Product Code. 13462204

Description

High affinity 5-HT2B receptor antagonist (pKi = 9.5). Displays 1000-fold selectivity for 5-HT2B with good bioavailability.

Chemical Identifiers

• CAS: 199864-86-3
• Molecular Weight (g/mol): 317.792
• Synonym: 4-4-fluoronaphthalen-1-yl-6-isopropylpyrimidin-2-amine hydrochloride, rs-127445 hydrochloride, 4-4-fluoro-1-naphthalenyl-6-1-methylethyl-2-pyrimidinamine hydrochloride, rs 127445 hydrochloride, 2-amino-4-4-fluoronaphth-1-yl-6-isopropylpyrimidine hydrochloride, mt 500 hydrochloride, rs127445 hydrochloride, rs-127445 hydrochloride hplc , powder, 2-amino-4-4-fluoronaphth-1-yl-6-isopropylpyrimidine monohydrochloride, 4-4-fluoronaphthalen-1-yl-6-isopropylpyrimidin-2-aminehydrochloride
• IUPAC Name: 4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine;hydrochloride

• Molecular Formula: C17H17ClFN3
• InChI Key: MKJPYBJBPRFMHL-UHFFFAOYSA-N
• PubChem CID: 9905058
• SMILES: CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N.Cl

Specifications

• Chemical Name or Material: RS 127445 hydrochloride
• CAS: 199864-86-3
• Synonym: 4-4-fluoronaphthalen-1-yl-6-isopropylpyrimidin-2-amine hydrochloride, rs-127445 hydrochloride, 4-4-fluoro-1-naphthalenyl-6-1-methylethyl-2-pyrimidinamine hydrochloride, rs 127445 hydrochloride, 2-amino-4-4-fluoronaphth-1-yl-6-isopropylpyrimidine hydrochloride, mt 500 hydrochloride, rs127445 hydrochloride, rs-127445 hydrochloride hplc , powder, 2-amino-4-4-fluoronaphth-1-yl-6-isopropylpyrimidine monohydrochloride, 4-4-fluoronaphthalen-1-yl-6-isopropylpyrimidin-2-aminehydrochloride
• SMILES: CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N.Cl
• Molecular Weight (g/mol): 317.792
• Formula Weight: 317.79

• Quantity: 10mg
• Molecular Formula: C17H17ClFN3
• InChI Key: MKJPYBJBPRFMHL-UHFFFAOYSA-N
• IUPAC Name: 4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine;hydrochloride
• PubChem CID: 9905058
• Percent Purity: >98%