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ROR gamma (t) Rat anti-Mouse, PE, Clone: B2D, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-6981-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15209269

  • £254.73 / 100µg


EU Stock 6
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Disclaimers:

For Research Use Only.


Description

Description

The B2D monoclonal antibody reacts with the mouse ROR gamma (t) protein. ROR gamma is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes ROR alpha and ROR beta. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. ROR gamma is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, ROR gamma t, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ “double-positive” thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs.

The ROR gamma t isoform differs from ROR gamma by three unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the ROR gamma and ROR gamma t isoforms.
Specifications

Specifications

ROR gamma (t)
B2D
PE
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Retinoid-Related Orphan Receptor gamma
IgG1
RUO
Primary
Murine