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Ro 51, Tocris Bioscience™

Potent P2X3, P2X2/3 antagonist

Brand:  RD Systems (Bio-Techne) 4391/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13464674

  • £183.48 / 10mg


Estimated Shipment
02-01-2019
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Description

Description

Potent, dual P2X3 and P2X2/3 antagonist (IC50 values are 2 and 5 nM for rP2X3 and hP2X2/3 respectively). Selective for P2X3 and P2X2/3 over other P2X receptors (IC50 values are > 10μM for P2X1, P2X2, P2X4, P2X5, and P2X7). Cell permeable.
Specifications

Chemical Identifiers

1050670-85-3
474.299
2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-yl amino propane-1,3-diol, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-yl amino propane-1,3-diol, compound 128 pmid: 26686393, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-ylamino propane-1,3-diol, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxy-phenoxy-pyrimidin-2-ylamino-propane-1,3-diol, 2-4-amino-5-5-iodo-4-methoxy-2-propan-2-ylphenoxy pyrimidin-2-yl amino propane-1,3-diol, 2-4-amino-5-5-iodo-4-methoxy-2-1-methylethyl phenoxy-2,4-pyrimidinyl amino-1,3-propanediol
2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propane-1,3-diol
C17H23IN4O4
PAYROHWFGZADBR-UHFFFAOYSA-N
24883277
CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)NC(CO)CO)I)OC

Specifications

Ro 51
1050670-85-3
2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-yl amino propane-1,3-diol, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-yl amino propane-1,3-diol, compound 128 pmid: 26686393, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxyphenoxy pyrimidin-2-ylamino propane-1,3-diol, 2-4-amino-5-5-iodo-2-isopropyl-4-methoxy-phenoxy-pyrimidin-2-ylamino-propane-1,3-diol, 2-4-amino-5-5-iodo-4-methoxy-2-propan-2-ylphenoxy pyrimidin-2-yl amino propane-1,3-diol, 2-4-amino-5-5-iodo-4-methoxy-2-1-methylethyl phenoxy-2,4-pyrimidinyl amino-1,3-propanediol
CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)NC(CO)CO)I)OC
474.299
474.29
10mg
C17H23IN4O4
PAYROHWFGZADBR-UHFFFAOYSA-N
2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propane-1,3-diol
24883277
>98%
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