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RN 1747, Tocris Bioscience™

Selective TRPV4 agonist

Brand:  Tocris (Bio-Techne) 374510

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13453534

  • £154.35 / 10mg

Estimated Shipment date
from Supplier 01-04-2020

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Description

Description

Selective TRPV4 agonist (EC50 values are 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively). Displays selectivity over other TRP channels (EC50 values are 0.77, >30, >30 and >100 μM for TRPV4, TRPM8, TRPV3 and TRPV1 receptors respectively). Also antagonizes TRPM8 at relevant concentrations (IC50 = 4 μM).
Specifications

Chemical Identifiers

1024448-59-6
395.858
4-chloro-2-nitro-1-4-benzylpiperazinyl sulfonyl benzene, 1-benzyl-4-4-chloro-2-nitrobenzenesulfonyl piperazine, d0a5ly, rn hplc, 1-4-chloro-2-nitrophenyl sulfonyl-4-benzylpiperazine, 1-benzyl-4-4-chloro-2-nitrophenyl sulfonylpiperazine, 1-4-chloro-2-nitrophenyl sulfonyl-4-benzylpiperazine;, 1-benzyl-4-4-chloro-2-nitrobenzene sulfonyl piperazine, 1-4-chloro-2-nitrophenyl sulfonyl-4-phenylmethyl-piperazine
1-benzyl-4-(4-chloro-2-nitrophenyl)sulfonylpiperazine
C17H18ClN3O4S
ZNLVYSJQUMALEO-UHFFFAOYSA-N
5068295
C1CN(CCN1CC2=CC=CC=C2)S(=O)(=O)C3=C(C=C(C=C3)Cl)[N+](=O)[O-]

Specifications

10mg
1024448-59-6
4-chloro-2-nitro-1-4-benzylpiperazinyl sulfonyl benzene, 1-benzyl-4-4-chloro-2-nitrobenzenesulfonyl piperazine, d0a5ly, rn hplc, 1-4-chloro-2-nitrophenyl sulfonyl-4-benzylpiperazine, 1-benzyl-4-4-chloro-2-nitrophenyl sulfonylpiperazine, 1-4-chloro-2-nitrophenyl sulfonyl-4-benzylpiperazine;, 1-benzyl-4-4-chloro-2-nitrobenzene sulfonyl piperazine, 1-4-chloro-2-nitrophenyl sulfonyl-4-phenylmethyl-piperazine
C1CN(CCN1CC2=CC=CC=C2)S(=O)(=O)C3=C(C=C(C=C3)Cl)[N+](=O)[O-]
395.858
395.87
RN 1747
C17H18ClN3O4S
ZNLVYSJQUMALEO-UHFFFAOYSA-N
1-benzyl-4-(4-chloro-2-nitrophenyl)sulfonylpiperazine
5068295
>98%
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