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RJR 2429 dihydrochloride, Tocris Bioscience™

Nicotinic receptor agonist

Brand:  Tocris (Bio-Techne) 127150

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13459033

  • £554.00 / 50mg


Estimated Shipment
31-08-2018
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Description

Description

Potent nAChR agonist that displays selectivity for α4β2 (Ki = 1 nM) and α1βγδ subtypes (EC50 values are 297 and 55 nM respectively). Induces dopamine release from striatal neurons (EC50 = 2 nM) and inhibits ion flux in thalamic neurons (IC50 = 154 nM). Also putative α3β4 agonist that potentiates catecholamine release.
Specifications

Chemical Identifiers

1021418-53-0
261.19
(±)-2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane dihydrochloride
C12H18Cl2N2
PIUNXHHZRIUBOV-UHFFFAOYSA-N
56972204

Specifications

RJR 2429 dihydrochloride
1021418-53-0
C12H18Cl2N2
PIUNXHHZRIUBOV-UHFFFAOYSA-N
2-pyridin-3-yl-1-azabicyclo[2.2.2]octane;dihydrochloride
56972204
50mg
>98%
(±)-2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane dihydrochloride
C1CN2CCC1CC2C3=CN=CC=C3.Cl.Cl
261.19
261.19
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