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enQuireBio™ Recombinant Mouse Leptin tA Protein

A cDNA sequence encoding the Leptin tA was constructed and used to recombinantly synthesize the protein.

£99.15 - £155.00

Specifications

Name Leptin tA Protein
Regulatory Status Research Use Only
Endotoxin Concentration < 1.0 EU per ug protein as determined by the LAL method.
Biological Activity Leptin Antagonist Triple Mutant Mouse Recombinant half-life in circulation after SC injection was over 20 hours. Leptin Antagonist Triple Mutant Mouse Recombinant is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Leptin Antagonist Triple Mutant Mouse Recombinant in vitro activity is 5-6 fold lower than the non-pegylated antagonist, though in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake.
Product Type Recombinant Protein
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15945098
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enQuireBio™
QP10764-5UG
5 μg
£99.15
5µg
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Estimated Shipment: 09-05-2024
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15935098
View Documents Promotion Details
enQuireBio™
QP10764-20UG
20 μg
£155.00
20µg
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Estimated Shipment: 09-05-2024
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Description

Description

Specifications

Specifications

Leptin tA Protein
< 1.0 EU per ug protein as determined by the LAL method.
Recombinant Protein
E. coli
The Mouse Leptin triple antagonist was lyophilized from a concentrated (0.65 mg/ml) solution with 0.003mM NaHCO3.
Research Use Only
Leptin Antagonist Triple Mutant Mouse Recombinant half-life in circulation after SC injection was over 20 hours. Leptin Antagonist Triple Mutant Mouse Recombinant is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Leptin Antagonist Triple Mutant Mouse Recombinant in vitro activity is 5-6 fold lower than the non-pegylated antagonist, though in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake.
Mouse
Untagged
Greater than 99.0% as determined by:(a) Gel filtration analysis. (b) Analysis by SDS-PAGE.
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