missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ TGF beta-1 Rat ELISA Kit

For the quantitative detection of rat TGF-beta1.

Brand:  Invitrogen™ BMS623-3TWO

386.68 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15542057

  • £580.00 / Pack of 2
Estimated Shipment: 10-04-2024
to see stock.
Add to basket

Includes: Aluminum pouch(es) with a Microwell Plate coated with monoclonal antibody to rat TGF-beta1
Biotin-Conjugate anti-rat TGF-beta1 polyclonal antibody
Streptavidin-HRP
Rat TGF-beta1 Standard lyophilized, 4000pg/mL upon reconstitution
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrat Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Adhesive Films

Description

Description

TGF beta-1 (TGFB1, Transforming Growth Factor Beta 1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its pro-domain. Activation of TGF beta-1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF beta-1, an amino-terminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP. TGF beta-1 helps regulates proliferation, differentiation, adhesion, migration in many cell types. Many cells have TGF beta receptors, and the protein positively and negatively regulates many other growth factors. TGF beta-1 is cleaved into a latency-associated peptide and a mature TGF beta-1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGF beta-1 homodimer. The mature peptide may also form heterodimers with other TGF beta family members. The gene for TGF beta-1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease and cystic fibrosis.
Specifications

Specifications

P17246
7.8 pg/mL
ELISA Kit
Rat
Colorimetric Microplate Reader
Tgfb
6.8%
HRP
RUO
2°C to 8°C
Rat
4 hr.
31.25-2,000 pg/mL
Biotin
Plasma, Serum, Supernatant
ELISA
59086
6.8%
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
2 x 96 Tests
Plasma, 20 μL; Serum, 20 μL; Supernatant, 20 μL
Camurati-Engelmann disease, DPD1
1 hr. 20 min.
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers